The pore domain of the nicotinic acetylcholine receptor: molecular modeling, pore dimensions, and electrostatics
The pore domain of the nicotinic acetylcholine receptor has been modeled as a bundle of five kinked M2 helices. Models were generated via molecular dynamics simulations incorporating restraints derived from 9-Å resolution cryoelectron microscopy data (Unwin, 1993; 1995), and from mutagenesis data th...
Autors principals: | , , |
---|---|
Altres autors: | |
Format: | Journal article |
Idioma: | English |
Publicat: |
Elsevier
1996
|
Matèries: |