CCR5 promoter polymorphisms in a Kenyan perinatal human immunodeficiency virus type 1 cohort: association with increased 2-year maternal mortality.

The CCR5 chemokine receptor acts as a coreceptor with CD4 to permit infection by primary macrophage-tropic human immunodeficiency virus type 1 (HIV-1) strains. The CCR5Delta32 mutation, which is associated with resistance to infection in homozygous individuals and delayed disease progression in hete...

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Váldodahkkit: John, G, Bird, T, Overbaugh, J, Nduati, R, Mbori-Ngacha, D, Rostron, T, Dong, T, Kostrikis, L, Richardson, B, Rowland-Jones, S
Materiálatiipa: Journal article
Giella:English
Almmustuhtton: 2001