Crystal structure of the RNA-dependent RNA polymerase from influenza C virus.
Negative-sense RNA viruses, such as influenza, encode large, multidomain RNA-dependent RNA polymerases that can both transcribe and replicate the viral RNA genome. In influenza virus, the polymerase (FluPol) is composed of three polypeptides: PB1, PB2 and PA/P3. PB1 houses the polymerase active site...
Main Authors: | , , , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
Nature Publishing Group
2015
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