Crystal structure of the RNA-dependent RNA polymerase from influenza C virus.
Negative-sense RNA viruses, such as influenza, encode large, multidomain RNA-dependent RNA polymerases that can both transcribe and replicate the viral RNA genome. In influenza virus, the polymerase (FluPol) is composed of three polypeptides: PB1, PB2 and PA/P3. PB1 houses the polymerase active site...
Main Authors: | Hengrung, N, Omari, K, Martin, I, Vreede, F, Cusack, S, Rambo, R, Vonrhein, C, Bricogne, G, Stuart, D, Grimes, J, Fodor, E |
---|---|
Formato: | Journal article |
Idioma: | English |
Publicado em: |
Nature Publishing Group
2015
|
Registos relacionados
-
Structure of the RNA-dependent RNA polymerase from influenza C virus
Por: Hengrung, N
Publicado em: (2014) -
The role of the influenza virus RNA polymerase in host shut-off.
Por: Vreede, F, et al.
Publicado em: (2010) -
Association of the influenza A virus RNA-dependent RNA polymerase with cellular RNA polymerase II.
Por: Engelhardt, O, et al.
Publicado em: (2005) -
Influenza virus inhibits RNA polymerase II elongation.
Por: Chan, A, et al.
Publicado em: (2006) -
RNA-free and ribonucleoprotein-associated influenza virus polymerases directly bind the serine-5 phosphorylated carboxyl-terminal domain of host RNA polymerase II
Por: Fodor, E, et al.
Publicado em: (2016)