Purine nucleotide metabolism regulates expression of the human immune ligand MICA
Expression of the cell-surface glycoprotein MHC class I polypeptide-related sequence A (MICA) is induced in dangerous, abnormal, or “stressed” cells, including cancer cells, virus-infected cells, and rapidly proliferating cells. MICA is recognized by the activating immune cell receptor natural kille...
Main Authors: | , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
American Society for Biochemistry and Molecular Biology
2017
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