A general copper-mediated nucleophilic 18F fluorination of arenes

A general copper-mediated nucleophilic 18F fluorination of arenes

Show other versions (1)

Molecules labeled with fluorine-18 are used as radiotracers for positron emission tomography. An important challenge is the labeling of arenes not amenable to aromatic nucleophilic substitution (SNAr) with [ 18F]F-. In the ideal case, the 18F fluorination of these substrates would be performed throu...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak:	Tredwell, M, Preshlock, S, Taylor, N, Gruber, S, Huiban, M, Passchier, J, Mercier, J, Génicot, C, Gouverneur, V
Formatua:	Journal article
Argitaratua:	2014

Antzeko izenburuak

A general copper-mediated nucleophilic 18F fluorination of arenes.
nork: Tredwell, M, et al.
Argitaratua: (2014)

Derisking the Cu-mediated (18)F-fluorination of heterocyclic positron emission tomography radioligands
nork: Taylor, N, et al.
Argitaratua: (2017)

18F labeling of arenes.
nork: Tredwell, M, et al.
Argitaratua: (2012)

Metal-free oxidative fluorination of phenols with [18F]fluoride.
nork: Gao, Z, et al.
Argitaratua: (2012)

Photoredox Nucleophilic (Radio)fluorination of Alkoxyamines
nork: Ortalli, S, et al.
Argitaratua: (2024)

Catalytic decarboxylative fluorination for the synthesis of tri- and difluoromethyl arenes.
nork: Mizuta, S, et al.
Argitaratua: (2013)

Simple procedure for the [F-18]trifluoromethylation of aryl and heteroaryl halides
nork: Huiban, M, et al.
Argitaratua: (2013)

Fluorous synthesis of 18F radiotracers with the [18F]fluoride ion: nucleophilic fluorination as the detagging process.
nork: Bejot, R, et al.
Argitaratua: (2009)

Copper-mediated nucleophilic 18F-radiolabelling of (hetero)arenes for applications in positron emission tomography
nork: Taylor, N
Argitaratua: (2017)

A broadly applicable [18F]trifluoromethylation of aryl and heteroaryl iodides for PET imaging.
nork: Huiban, M, et al.
Argitaratua: (2013)

Transition metal catalysis and nucleophilic fluorination.
nork: Hollingworth, C, et al.
Argitaratua: (2012)

Electrophilic fluorination of organosilanes.
nork: Tredwell, M, et al.
Argitaratua: (2006)

PET F-18-CHEMISTRY
nork: Tredwell, M, et al.
Argitaratua: (2011)

Palladium-catalyzed allylic fluorination.
nork: Hollingworth, C, et al.
Argitaratua: (2011)

Bridging the gaps in (18)F PET tracer development
nork: Campbell, MG, et al.
Argitaratua: (2016)

1.5 Fluorine in Medicinal Chemistry: Importance of Chirality
nork: Tredwell, M, et al.
Argitaratua: (2012)

ORGN 257-Electrophilic fluorination of acyclic chiral allylsilanes
nork: Tredwell, M, et al.
Argitaratua: (2006)

New methods for nucleophilic fluorination
nork: Cresswell, A
Argitaratua: (2011)

Calcium fluoride for nucleophilic fluorination
nork: Patel, C
Argitaratua: (2024)

Single and double stereoselective fluorination of (E)-allylsilanes
nork: Sawicki, M, et al.
Argitaratua: (2007)

Single and double stereoselective fluorination of (E)-allylsilanes.
nork: Sawicki, M, et al.
Argitaratua: (2007)

Fluorine-directed diastereoselective iodocyclizations.
nork: Tredwell, M, et al.
Argitaratua: (2008)

Regiodivergent nucleophilic fluorination under hydrogen bonding catalysis: a computational and experimental study
nork: Horwitz, MA, et al.
Argitaratua: (2023)

Asymmetric nucleophilic fluorination under hydrogen bonding phase-transfer catalysis
nork: Pupo, G, et al.
Argitaratua: (2018)

Single and double stereoselective fluorination of (E)-allylsilanes
nork: Marcin Sawicki, et al.
Argitaratua: (2007-10-01)

Pd-Catalyzed Nucleophilic Fluorination of Aryl Bromides
nork: Lee, Hong Geun, et al.
Argitaratua: (2015)

Nucleophilic fluoroalkylation/cyclization route to fluorinated phthalides
nork: Masanori Inaba, et al.
Argitaratua: (2018-01-01)

Synthesis of novel enantiopure fluorinated building blocks from acyclic chiral allylsilanes.
nork: Tredwell, M, et al.
Argitaratua: (2005)

A convergent approach for the synthesis of fluorinated sphingosine analogues
nork: Teare, H, et al.
Argitaratua: (2007)

[18F]fluorination of an arylboronic ester using [18F]selectfluor bis(triflate): application to 6-[18F]fluoro-L-DOPA.
nork: Stenhagen, I, et al.
Argitaratua: (2013)

Ionic Liquids as Organocatalysts for Nucleophilic Fluorination: Concepts and Perspectives
nork: Young-Ho Oh, et al.
Argitaratua: (2022-09-01)

Harnessing Ionic Interactions and Hydrogen Bonding for Nucleophilic Fluorination
nork: Young-Ho Oh, et al.
Argitaratua: (2020-02-01)

Synthesis of 18F-difluoromethylarenes using aryl boronic acids, ethyl bromofluoroacetate and [18F]fluoride
nork: Sap, J, et al.
Argitaratua: (2019)

Synthesis and reactivity of (18)F-labeled α,α-Difluoro-α-(aryloxy)acetic acids.
nork: Khotavivattana, T, et al.
Argitaratua: (2017)

18F-trifluoromethylation of unmodified peptides with 5-18F-(trifluoromethyl)dibenzothiophenium trifluoromethanesulfonate
nork: Verhoog, S, et al.
Argitaratua: (2018)

Fluorination of an arylboronic ester using [18F]selectfluor bis(triflate): Application to 6-[18F]fluoro-l-DOPA
nork: Stenhagen, I, et al.
Argitaratua: (2013)

New methods in 18F-fluorination and fluoroalkylation
nork: Ford, J
Argitaratua: (2024)

Theoretical study on the nucleophilic fluoroalkylation of propylene oxide with fluorinated sulfones
nork: Han Ling-Li, et al.
Argitaratua: (2013-01-01)

OXETANE NUCLEOSIDES WITH FLUORINE AND AZIDE SUBSTITUENTS - NUCLEOPHILIC DISPLACEMENTS ON AN OXETANE RING
nork: Wang, Y, et al.
Argitaratua: (1991)

A convergent approach for the synthesis of fluorinated sphingosine analogues
nork: Harriet Teare, et al.
Argitaratua: (2007-03-01)