Impact of MHC class I diversity on immune control of immunodeficiency virus replication.

The recent failure of the T-cell-based HIV vaccine trial led by Merck and Co., Inc. prompts the urgent need to refocus on the question of which T-cell responses are required to control HIV replication. The well-described association between the expression of particular MHC class I molecules and succ...

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Detalhes bibliográficos
Principais autores: Goulder, P, Watkins, D
Formato: Journal article
Idioma:English
Publicado em: 2008