Sensory fibres expressing capsaicin receptor TRPV1 in patients with rectal hypersensitivity and faecal urgency.

BACKGROUND: Faecal urgency and incontinence with rectal hypersensitivity is a distressing, unexplained disorder that is inadequately treated. We aimed to determine whether expression of the heat and capsaicin receptor vanilloid receptor 1 (TRPV1 or VR1) was changed in rectal sensory fibres, and to c...

Full description

Bibliographic Details
Main Authors: Chan, C, Facer, P, Davis, J, Smith, G, Egerton, J, Bountra, C, Williams, N, Anand, P
Format: Journal article
Language:English
Published: 2003