Sensory fibres expressing capsaicin receptor TRPV1 in patients with rectal hypersensitivity and faecal urgency.

BACKGROUND: Faecal urgency and incontinence with rectal hypersensitivity is a distressing, unexplained disorder that is inadequately treated. We aimed to determine whether expression of the heat and capsaicin receptor vanilloid receptor 1 (TRPV1 or VR1) was changed in rectal sensory fibres, and to c...

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Hlavní autoři: Chan, C, Facer, P, Davis, J, Smith, G, Egerton, J, Bountra, C, Williams, N, Anand, P
Médium: Journal article
Jazyk:English
Vydáno: 2003