Cytokines induced during chronic hepatitis B virus infection promote a pathway for NK cell-mediated liver damage.

Hepatitis B virus (HBV) causes chronic infection in more than 350 million people worldwide. It replicates in hepatocytes but is non-cytopathic; liver damage is thought to be immune mediated. Here, we investigated the role of innate immune responses in mediating liver damage in patients with chronic...

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Detalhes bibliográficos
Main Authors: Dunn, C, Brunetto, M, Reynolds, G, Christophides, T, Kennedy, P, Lampertico, P, Das, A, Lopes, A, Borrow, P, Williams, K, Humphreys, E, Afford, S, Adams, D, Bertoletti, A, Maini, M
Formato: Journal article
Idioma:English
Publicado em: 2007