Induced sputum and bronchial mucosal expression of interleukin-13 is not increased in chronic obstructive pulmonary disease.

BACKGROUND: The Th2 cytokine interleukin-13 (IL-13) has been implicated in the pathogenesis of chronic obstructive pulmonary disease (COPD). We sought to examine IL-13 expression in COPD subjects in induced sputum and bronchus specimens. We hypothesized that inflammatory cells expressing IL-13 local...

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Bibliographic Details
Main Authors: Saha, S, Mistry, V, Siva, R, Parker, D, May, R, Bradding, P, Pavord, I, Brightling, C
Format: Journal article
Language:English
Published: 2008