Structural principles controlling HIV envelope glycosylation

The heavily glycosylated, trimeric HIV-1 envelope (Env) protein is the sole viral protein exposed on the HIV-1 virion surface and is thus a main focus of antibody-mediated vaccine development. Dense glycosylation at the outer domain of Env constrains normal enzymatic processing, stalling the glycans...

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Bibliographic Details
Main Authors: Behrens, A, Crispin, M
Format: Journal article
Published: Elsevier 2017