Structural principles controlling HIV envelope glycosylation
The heavily glycosylated, trimeric HIV-1 envelope (Env) protein is the sole viral protein exposed on the HIV-1 virion surface and is thus a main focus of antibody-mediated vaccine development. Dense glycosylation at the outer domain of Env constrains normal enzymatic processing, stalling the glycans...
Main Authors: | Behrens, A, Crispin, M |
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Format: | Journal article |
Published: |
Elsevier
2017
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