Bmp7 maintains undifferentiated kidney progenitor population and determines nephron numbers at birth

The number of nephrons, the functional units of the kidney, varies among individuals. A low nephron number at birth is associated with a risk of hypertension and the progression of renal insufficiency. The molecular mechanisms determining nephron number during embryogenesis have not yet been clarifi...

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Bibliographic Details
Main Authors: Tomita, M, Asada, M, Asada, N, Nakamura, J, Oguchi, A, Higashi, A, Endo, S, Robertson, E, Kimura, T, Kita, T, Economides, A, Kreidberg, J, Yanagita, M
Format: Journal article
Language:English
Published: Public Library of Science 2013