A numerical guide to the solution of the bi-domain equations of cardiac electrophysiology.

Simulation of cardiac electrical activity using the bi-domain equations can be a massively computationally demanding problem. This study provides a comprehensive guide to numerical bi-domain modelling. Each component of bi-domain simulations--discretization, ODE-solution, linear system solution, and...

תיאור מלא

מידע ביבליוגרפי
Main Authors: Pathmanathan, P, Bernabeu, M, Bordas, R, Cooper, J, Garny, A, Pitt-Francis, J, Whiteley, J, Gavaghan, D
פורמט: Journal article
שפה:English
יצא לאור: 2010
תיאור
סיכום:Simulation of cardiac electrical activity using the bi-domain equations can be a massively computationally demanding problem. This study provides a comprehensive guide to numerical bi-domain modelling. Each component of bi-domain simulations--discretization, ODE-solution, linear system solution, and parallelization--is discussed, and previously-used methods are reviewed, new methods are proposed, and issues which cause particular difficulty are highlighted. Particular attention is paid to the choice of stimulus currents, compatibility conditions for the equations, the solution of singular linear systems, and convergence of the numerical scheme.