Imatinib radiosensitizes bladder cancer by targeting homologous recombination.
Radiotherapy is a major treatment modality used to treat muscle-invasive bladder cancer, with patient outcomes similar to surgery. However, radioresistance is a significant factor in treatment failure. Cell-free extracts of muscle-invasive bladder tumors are defective in nonhomologous end-joining (N...
मुख्य लेखकों: | Qiao, B, Kerr, M, Groselj, B, Teo, M, Knowles, M, Bristow, R, Phillips, R, Kiltie, A |
---|---|
स्वरूप: | Journal article |
भाषा: | English |
प्रकाशित: |
2013
|
समान संसाधन
-
Targeting homologous recombination using imatinib results in enhanced tumor cell chemosensitivity and radiosensitivity.
द्वारा: Choudhury, A, और अन्य
प्रकाशित: (2009) -
E3 ligase cIAP2 mediates downregulation of MRE11 and radiosensitization in response to HDAC inhibition in bladder cancer
द्वारा: Nicholson, J, और अन्य
प्रकाशित: (2017) -
Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination
द्वारा: Nina M. S. Gustafsson, और अन्य
प्रकाशित: (2018-09-01) -
Radiosensitisation of bladder cancer cells by panobinostat is modulated by Ku80 expression
द्वारा: Groselj, B, और अन्य
प्रकाशित: (2013) -
Radiosensitisation of bladder cancer cells by panobinostat is modulated by Ku80 expression.
द्वारा: Groselj, B, और अन्य
प्रकाशित: (2013)