Imatinib radiosensitizes bladder cancer by targeting homologous recombination.

Imatinib radiosensitizes bladder cancer by targeting homologous recombination.

Radiotherapy is a major treatment modality used to treat muscle-invasive bladder cancer, with patient outcomes similar to surgery. However, radioresistance is a significant factor in treatment failure. Cell-free extracts of muscle-invasive bladder tumors are defective in nonhomologous end-joining (N...

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Những tác giả chính:	Qiao, B, Kerr, M, Groselj, B, Teo, M, Knowles, M, Bristow, R, Phillips, R, Kiltie, A
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	2013

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