Convenient synthesis of enantiopure cyclic alpha-hydroxyalkyl alpha-amino esters

The preparation of cyclic α-hydroxyalkyl α-amino esters, the ring size of which varies varies from 4 to 7 members, in enantiopure form is readily achieved by intramolecular alkylative cyclisation of oxazolidine precursors.

Bibliographic Details
Main Authors: Andrews, MD, Brewster, A, Moloney, M, Owen, K
Format: Journal article
Language:English
Published: 1996