Relationship between changes in thymic emigrants and cell-associated HIV-1 DNA in HIV-1-infected children initiating antiretroviral therapy.

OBJECTIVES AND METHODS: To investigate the relationship between cell-associated HIV-1 dynamics and recent thymic T-cell emigrants, HIV-1 DNA and T-cell receptor rearrangement excision circles (TREC, a marker of recent thymic emigrants) were measured in peripheral blood mononuclear cells in 181 samp...

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Bibliographic Details
Main Authors: De Rossi, A, Walker, A, De Forni, D, Klein, N, Gibb, D
Format: Journal article
Language:English
Published: 2005