Crystal structure of a DNA duplex containing 8-hydroxydeoxyguanine-adenine base pairs.

The crystal structure of the oligonucleotide d(CGCAAATTO8GGCG), containing the chemically modified base 8-hydroxydeoxyguanine (O8G), has been determined at 2.5-A resolution and refined to a crystallographic R-factor of 16.8%. The B-type DNA helix contains standard Watson-Crick base pairs except at t...

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Bibliographic Details
Main Authors: McAuley-Hecht, K, Leonard, G, Gibson, N, Thomson, J, Watson, W, Hunter, W, Brown, T
Format: Journal article
Language:English
Published: 1994