Highly functionalized cyclic and bicyclic β−amino acids from sugar β−nitroesters

The synthesis of highly functionalized bicyclic and cyclic β-amino acids from β-nitrosugars is reported. Specifically, our strategy for the synthesis of polyhydroxylated cyclopentane β-amino acids via the intramolecular C-alkylation of 6-nitro-2-O-triflates of furanosides has been applied to the pre...

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Bibliographic Details
Main Authors: Otero, JM, Estévez, AM, Estévez, JC, Fleet, GWJ, Estévez, RJ
Format: Journal article
Language:English
Published: Elsevier 2019