Rare event detection using error-corrected DNA and RNA sequencing

Conventional next-generation sequencing techniques (NGS) have allowed for immense genomic characterization for over a decade. Specifically, NGS has been used to analyze the spectrum of clonal mutations in malignancy. Though far more efficient than traditional Sanger methods, NGS struggles with ident...

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Bibliographic Details
Main Authors: Wong, WH, Tong, RS, Young, AL, Druley, TE
Format: Journal article
Language:English
Published: MYJoVE Corporation 2019