Rare event detection using error-corrected DNA and RNA sequencing

Conventional next-generation sequencing techniques (NGS) have allowed for immense genomic characterization for over a decade. Specifically, NGS has been used to analyze the spectrum of clonal mutations in malignancy. Though far more efficient than traditional Sanger methods, NGS struggles with ident...

Полное описание

Библиографические подробности
Главные авторы: Wong, WH, Tong, RS, Young, AL, Druley, TE
Формат: Journal article
Язык:English
Опубликовано: MYJoVE Corporation 2019