Heregulin-induced epigenetic regulation of the utrophin-A promoter.
Utrophin is the autosomal homolog of dystrophin, the product of the Duchenne's muscular dystrophy (DMD) locus. Utrophin is of therapeutic interest since its over-expression can compensate dystrophin's absence. Utrophin is enriched at neuromuscular junctions due to heregulin-mediated utroph...
Главные авторы: | , , , , , , , |
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Формат: | Journal article |
Язык: | English |
Опубликовано: |
2007
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