TNF blockade maintains an IL-10+ phenotype in human effector CD4+ and CD8+ T cells

CD4+ and CD8+ effector T cell subpopulations can display regulatory potential characterized by expression of the prototypically anti-inflammatory cytokine IL-10. However, the underlying cellular mechanisms that regulate expression of IL-10 in different T cell subpopulations are not yet fully elucida...

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Bibliographic Details
Main Authors: Roberts, CA, Durham, LE, Fleskens, V, Evans, HG, Taams, LS
Format: Journal article
Language:English
Published: Frontiers Media 2018