Tetrahydrobiopterin (BH4), a cofactor for nNOS, restores gastric emptying and nNOS expression in female diabetic rats.

Gastroparesis is a debilitating disease predominantly affecting young women. Recently, dysregulation of neuronal nitric oxide synthase (nNOS) in myenteric plexus neurons has been implicated for delayed solid gastric emptying/gastroparesis in diabetic patients. In this study, we have explored the rol...

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Bibliographic Details
Main Authors: Gangula, P, Mukhopadhyay, S, Ravella, K, Cai, S, Channon, K, Garfield, R, Pasricha, P
Format: Journal article
Language:English
Published: 2010