RADVAN: a randomised phase 2 trial of WBRT plus vandetanib for melanoma brain metastases - results and lessons learnt

Brain metastases occur in up to 75% of patients with advanced melanoma. Most are treated with whole-brain radiotherapy (WBRT), with limited effectiveness. Vandetanib, an inhibitor of vascular endothelial growth factor receptor, epidermal growth factor receptor and rearranged during transfection tyro...

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Bibliographic Details
Main Authors: Gupta, A, Roberts, C, Tysoe, F, Goff, M, Nobes, J, Lester, J, Marshall, E, Corner, C, Wolstenholme, V, Kelly, C, Wise, A, Collins, L, Love, S, Woodward, M, Salisbury, A, Middleton, M
Format: Journal article
Language:English
Published: Cancer Research UK 2016