Asymmetric de novo synthesis of fluorinated D-glucitol and D-mannitol analogues

A highly efficient anti-SE2′ electrophilic fluorination of enantioenriched allylsilanes a subsequent dihydroxylation of the resulting allylic fluorides were used as key steps for the synthesis of three fluorinated carbohydrate analogues, 1,5-di-O-benzyl-2-deoxy-2-fluoro-d-glucitol, 2,6-di-O-benzyl-5...

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Bibliographic Details
Main Authors: Giuffredi, G, Purser, S, Sawicki, M, Thompson, A, Gouverneur, V
Format: Journal article
Language:English
Published: 2009