Late-Stage Trifluoromethylation

Late-Stage Trifluoromethylation

<p>This thesis is concerned with the development of methodology for late-stage trifluoromethylation of complex molecules.</p> <p><strong>Chapter 1</strong> introduces the concept of late-stage trifluoromethylations and details the effect that substitution of a CF<sub...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoir:	Verhoog, S
Rannpháirtithe:	Gouverneur, V
Formáid:	Tráchtas
Teanga:	English
Foilsithe / Cruthaithe:	2016

Míreanna comhchosúla

18F-trifluoromethylation of unmodified peptides with 5-18F-(trifluoromethyl)dibenzothiophenium trifluoromethanesulfonate
de réir: Verhoog, S, et al.
Foilsithe / Cruthaithe: (2018)

Trifluoromethylation of allylsilanes under copper catalysis.
de réir: Mizuta, S, et al.
Foilsithe / Cruthaithe: (2012)

Trifluoromethylation of allylsilanes under photoredox catalysis.
de réir: Mizuta, S, et al.
Foilsithe / Cruthaithe: (2013)

Redox chemistry of trifluoromethyl sulfonium salts as CF3 radical sources
de réir: Mizuta, S, et al.
Foilsithe / Cruthaithe: (2013)

Synthesis and trifluoromethylation of allylsilanes
de réir: Galicia Lopez, O
Foilsithe / Cruthaithe: (2013)

Trifluoromethyl-substituted tetrathiafulvalenes
de réir: Olivier Jeannin, et al.
Foilsithe / Cruthaithe: (2015-05-01)

Reaction of (trifluoromethyl)trimethylsilane with oxazolidin-5-ones: Synthesis of peptidic and nonpeptidic trifluoromethyl ketones
de réir: Walter, M, et al.
Foilsithe / Cruthaithe: (1998)

Progress in copper-catalyzed trifluoromethylation
de réir: Guan-bao Li, et al.
Foilsithe / Cruthaithe: (2018-01-01)

Visible Light Promotes Cascade Trifluoromethylation/Cyclization, Leading to Trifluoromethylated Polycyclic Quinazolinones, Benzimidazoles and Indoles
de réir: Ransong Ma, et al.
Foilsithe / Cruthaithe: (2022-12-01)

Copper-Catalyzed Trifluoromethylation of Alkoxypyridine Derivatives
de réir: Nandor Gyorfi, et al.
Foilsithe / Cruthaithe: (2020-10-01)

Synthesis of Trifluoromethylated Monoterpene Amino Alcohols
de réir: Polina A. Petrova, et al.
Foilsithe / Cruthaithe: (2022-10-01)

Langlois Reagent: An Efficient Trifluoromethylation Reagent
de réir: K. Anusha, et al.
Foilsithe / Cruthaithe: (2023-02-01)

Nucleophilic trifluoromethylation of some polycyclic ketones
de réir: Jarosław Romański, et al.
Foilsithe / Cruthaithe: (2007-03-01)

Nucleophilic trifluoromethylation of carbonyl compounds and derivatives
de réir: Gloria Rubiales, et al.
Foilsithe / Cruthaithe: (2014-01-01)

Application of fluoroform in trifluoromethylation and diﬂuoromethylation reactions
de réir: Cai Zhang
Foilsithe / Cruthaithe: (2017-03-01)

The Palladium-Catalyzed Trifluoromethylation of Aryl Chlorides
de réir: Cho, Eun Jin, et al.
Foilsithe / Cruthaithe: (2013)

Copper-Catalyzed Trifluoromethylation of Unactivated Olefins
de réir: Parsons, Andrew T., et al.
Foilsithe / Cruthaithe: (2013)

The Palladium-Catalyzed Trifluoromethylation of Vinyl Sulfonates
de réir: Cho, Eun Jin, et al.
Foilsithe / Cruthaithe: (2013)

Gas/Liquid‐Phase Micro‐Flow Trifluoromethylation using Fluoroform: Trifluoromethylation of Aldehydes, Ketones, Chalcones, and N‐Sulfinylimines
de réir: Kazuki Hirano, et al.
Foilsithe / Cruthaithe: (2019-04-01)

Gas/Liquid‐Phase Micro‐Flow Trifluoromethylation using Fluoroform: Trifluoromethylation of Aldehydes, Ketones, Chalcones, and N‐Sulfinylimines
de réir: Kazuki Hirano, et al.
Foilsithe / Cruthaithe: (2019-04-01)

1-(Pyridin-2-yl)-2-[2-(trifluoromethyl)benzyl]-3-[2-(trifluoromethyl)phenyl]propan-1-one
de réir: Muhammad Naveed Umar, et al.
Foilsithe / Cruthaithe: (2012-03-01)

Improved Synthesis of 2‑Trifluoromethyl-10-aminopropylphenothiazine: Making 2‑Trifluoromethyl-10-aminopropylphenothiazine Readily Available for Calmodulin Purification
de réir: Josiah W. Johnson, et al.
Foilsithe / Cruthaithe: (2018-11-01)

Selective radical trifluoromethylation of native residues in proteins
de réir: Imiołek, M, et al.
Foilsithe / Cruthaithe: (2018)

Visible-light-induced trifluoromethylation of allylic alcohols
de réir: Li, Bowen, et al.
Foilsithe / Cruthaithe: (2022)

Access to cyclopropanes with geminal trifluoromethyl and difluoromethylphosphonate groups
de réir: Ita Hajdin, et al.
Foilsithe / Cruthaithe: (2023-04-01)

Antibacterial Activity of Salicylanilide 4-(Trifluoromethyl)-benzoates
de réir: Jiřina Stolaříková, et al.
Foilsithe / Cruthaithe: (2013-03-01)

Methyl 2-[4-(trifluoromethyl)phenylsulfanyl]benzoate
de réir: Thammarse S. Yamuna, et al.
Foilsithe / Cruthaithe: (2013-11-01)

Electrochemical O-trifluoromethylation of electron-deficient phenols
de réir: Johannes Bernd, et al.
Foilsithe / Cruthaithe: (2021-12-01)

Synthesis of new triazole-based trifluoromethyl scaffolds
de réir: Michela Martinelli, et al.
Foilsithe / Cruthaithe: (2008-05-01)

Iron(II)-Catalyzed Trifluoromethylation of Potassium Vinyltrifluoroborates
de réir: Parsons, Andrew T., et al.
Foilsithe / Cruthaithe: (2013)

18F-trifluoromethanesulfinate enables direct C–H 18F-trifluoromethylation of native aromatic residues in peptides
de réir: Kee, C, et al.
Foilsithe / Cruthaithe: (2020)

Highly diastereoselective synthesis of trifluoromethyl indolines by interceptive benzylic decarboxylative cycloaddition of nonvinyl, trifluoromethyl benzoxazinanones with sulfur ylides under palladium catalysis
de réir: Punna, N, et al.
Foilsithe / Cruthaithe: (2018)

Catalytic asymmetric conjugate addition of mercaptans to β-substituted-β-trifluoromethyl oxazolidinone enoates : access to chiral trifluoromethylated tertiary thioethers and thiols
de réir: Chen, Wenchao, et al.
Foilsithe / Cruthaithe: (2014)

Catalytic asymmetric conjugate addition of mercaptans to β-substituted-β-trifluoromethyl oxazolidinone enoates: access to chiral trifluoromethylated tertiary thioethers and thiols
de réir: Chen, Wenchao, et al.
Foilsithe / Cruthaithe: (2014)

Controllable Synthesis of Trifluoromethyl- or <i>gem</i>-Difluorovinyl-containing Analogues of Neonicotinoids by the Reaction of α-(Trifluoromethyl)styrenes with 2-Nitroimino-imidazolidine
de réir: Jingjing He, et al.
Foilsithe / Cruthaithe: (2023-04-01)

Tetrakis[3,5-bis-(trifluoromethyl)phenyl]silane
de réir: Agnew, C, et al.
Foilsithe / Cruthaithe: (2006)

Copper-catalyzed olefinic trifluoromethylation of enamides at room temperature
de réir: Feng, Chao, et al.
Foilsithe / Cruthaithe: (2013)

Introducing Weakly Ligated Tris(trifluoromethyl)copper(III)
de réir: Dr. Vladimir Motornov, et al.
Foilsithe / Cruthaithe: (2024-03-01)

Recent Advances on the Halo- and Cyano-Trifluoromethylation of Alkenes and Alkynes
de réir: Bo Fu, et al.
Foilsithe / Cruthaithe: (2021-11-01)

Trifluoromethylated Quinolone-Hydantoin Hybrids: Synthesis and Antibacterial Evaluation
de réir: Akhil Mahajan, et al.
Foilsithe / Cruthaithe: (2022-07-01)