Doxycycline alters the porcine renal proteome and degradome during hypothermic machine perfusion

Ischemia-reperfusion injury (IRI) is a hallmark for tissue injury in donation after circulatory death (DCD) kidneys. The implementation of hypothermic machine perfusion (HMP) provides a platform for improved preservation of DCD kidneys. Doxycycline administration has shown protective effects during...

Full description

Bibliographic Details
Main Authors: van Leeuwen, L, Venema, LH, Heilig, R, Leuvenink, HGD, Kessler, BM
Format: Journal article
Language:English
Published: MDPI 2022