The PR/SET domain zinc finger protein Prdm4 regulates gene expression in embryonic stem cells but plays a nonessential role in the developing mouse embryo.

Prdm4 is a highly conserved member of the Prdm family of PR/SET domain zinc finger proteins. Many well-studied Prdm family members play critical roles in development and display striking loss-of-function phenotypes. Prdm4 functional contributions have yet to be characterized. Here, we describe its w...

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Autors principals: Bogani, D, Morgan, M, Nelson, A, Costello, I, McGouran, J, Kessler, B, Robertson, E, Bikoff, E
Format: Journal article
Idioma:English
Publicat: 2013