A coalescent-based method for detecting and estimating recombination from gene sequences.
Determining the amount of recombination in the genealogical history of a sample of genes is important to both evolutionary biology and medical population genetics. However, recurrent mutation can produce patterns of genetic diversity similar to those generated by recombination and can bias estimates...
Главные авторы: | McVean, G, Awadalla, P, Fearnhead, P |
---|---|
Формат: | Journal article |
Язык: | English |
Опубликовано: |
2002
|
Схожие документы
-
Approximating the coalescent with recombination.
по: Mcvean, G, и др.
Опубликовано: (2005) -
Application of coalescent methods to reveal fine-scale rate variation and recombination hotspots.
по: Fearnhead, P, и др.
Опубликовано: (2004) -
Recombination rate estimation in the presence of hotspots.
по: Auton, A, и др.
Опубликовано: (2007) -
Estimating recombination rates from genetic variation in humans.
по: Auton, A, и др.
Опубликовано: (2012) -
Estimating recombination rates from population-genetic data.
по: Stumpf, M, и др.
Опубликовано: (2003)