Characterisation of influenza A viruses with mutations in segment 5 packaging signals.

Influenza A virus vRNA segments contain specific packaging signals at their termini that overlap the coding regions. To further characterise segment 5 packaging signals, we introduced synonymous mutations into the terminal coding regions of the vRNA and characterised the replicative fitness of the r...

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Bibliographic Details
Main Authors: Hutchinson, E, Wise, H, Kudryavtseva, K, Curran, MD, Digard, P
Format: Journal article
Language:English
Published: 2009