Prevalence of CARD15/NOD2 mutations in Caucasian healthy people.

BACKGROUND: Crohn's disease (CD) has been associated with CARD15/NOD2 mutations in Caucasians. The R702W, G908R, and 1007fs mutations represent 82% of the mutated chromosomes. The relative risk of developing CD in homozygous or compound heterozygous people has been estimated as between 10 and...

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Main Authors: Hugot, J, Zaccaria, I, Cavanaugh, J, Yang, H, Vermeire, S, Lappalainen, M, Schreiber, S, Annese, V, Jewell, D, Fowler, E, Brant, SR, Silverberg, MS, Cho, J, Rioux, J, Satsangi, J, Parkes, M
Format: Journal article
Language:English
Published: 2007