Sequestration and microvascular congestion are associated with coma in human cerebral malaria.

The pathogenesis of coma in severe Plasmodium falciparum malaria remains poorly understood. Obstruction of the brain microvasculature because of sequestration of parasitized red blood cells (pRBCs) represents one mechanism that could contribute to coma in cerebral malaria. Quantitative postmortem mi...

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Bibliographic Details
Main Authors: Ponsford, M, Medana, I, Prapansilp, P, Hien, T, Lee, S, Dondorp, A, Esiri, M, Day, N, White, N, Turner, G
Format: Journal article
Language:English
Published: 2012