Cytotoxic T-lymphocyte escape mutations identified by HLA association favor those which escape and revert rapidly.

Identifying human immunodeficiency virus (HIV) immune escape mutations has implications for understanding the impact of host immunity on pathogen evolution and guiding the choice of vaccine antigens. One means of identifying cytotoxic-T-lymphocyte (CTL) escape mutations is to search for statistical...

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Bibliographic Details
Main Authors: Fryer, H, Frater, J, Duda, A, Palmer, D, Phillips, R, Mclean, A
Format: Journal article
Language:English
Published: 2012