Dopamine-mediated volume transmission in midbrain is regulated by distinct extracellular geometry and uptake.

Somatodendritic release of dopamine (DA) in midbrain is, at least in part, nonsynaptic; moreover, midbrain DA receptors are predominantly extrasynaptic. Thus somatodendritic DA mediates volume transmission, with an efficacy regulated by the diffusion and uptake characteristics of the local extracell...

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Váldodahkkit: Cragg, S, Nicholson, C, Kume-Kick, J, Tao, L, Rice, M
Materiálatiipa: Journal article
Giella:English
Almmustuhtton: 2001