Restoration of spatial working memory by genetic rescue of GluR-A-deficient mice.

Gene-targeted mice lacking the AMPA receptor subunit GluR-A (also called GluR1 encoded by the gene Gria1,) have deficits in hippocampal CA3-CA1 long-term potentiation (LTP) and have profoundly impaired hippocampus-dependent spatial working memory (SWM) tasks, although their spatial reference memory...

Полное описание

Библиографические подробности
Главные авторы: Schmitt, W, Sprengel, R, Mack, V, Draft, R, Seeburg, P, Deacon, R, Rawlins, J, Bannerman, D
Формат: Journal article
Язык:English
Опубликовано: 2005