Restoration of spatial working memory by genetic rescue of GluR-A-deficient mice.
Gene-targeted mice lacking the AMPA receptor subunit GluR-A (also called GluR1 encoded by the gene Gria1,) have deficits in hippocampal CA3-CA1 long-term potentiation (LTP) and have profoundly impaired hippocampus-dependent spatial working memory (SWM) tasks, although their spatial reference memory...
Main Authors: | , , , , , , , |
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格式: | Journal article |
语言: | English |
出版: |
2005
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