Evaluation of an In Silico Cardiac Safety Assay: Using Ion Channel Screening Data to Predict QT Interval Changes in the Rabbit Ventricular Wedge
<h3>Introduction</h3> Drugs that prolong the QT interval on the electrocardiogram present a major safety concern for pharmaceutical companies and regulatory agencies. Despite a range of assays performed to assess compound effects on the QT interval, QTprolongation remains a major cause o...
| Main Authors: | , , , , , , |
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| Format: | Journal article |
| Izdano: |
2013
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