Chemical probes for bromodomains outside the BET family

Chemical probes for bromodomains outside the BET family

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Brennan, P, Martin, S, Monteiro, O, Fedorov, O, Knapp, S, Hay, D, Wells, C, Filippakopoulos, P, Picaud, S, Muller-Knapp, S, Keates, T, Yapp, C, Philpott, M, Schofield, C, Burgess-Brown, N, Shrestha, L, Strain-Damerell, C
Μορφή:	Conference item
Έκδοση:	2013

Παρόμοια τεκμήρια

Developing chemical probes for the BET bromodomains
ανά: Hewings, D, κ.ά.
Έκδοση: (2012)

The design and synthesis of 5-and 6-isoxazolylbenzimidazoles as selective inhibitors of the BET bromodomains
ανά: Hay, D, κ.ά.
Έκδοση: (2013)

RVX-208, an inhibitor of BET transcriptional regulators with selectivity for the second bromodomain.
ανά: Picaud, S, κ.ά.
Έκδοση: (2013)

RVX-208, an inhibitor of BET transcriptional regulators with selectivity for the second bromodomain
ανά: Picaud, S, κ.ά.
Έκδοση: (2013)

[1,2,4]triazolo[4,3-a]phthalazines: inhibitors of diverse bromodomains.
ανά: Fedorov, O, κ.ά.
Έκδοση: (2014)

Benzodiazepines and benzotriazepines as protein interaction inhibitors targeting bromodomains of the BET family.
ανά: Filippakopoulos, P, κ.ά.
Έκδοση: (2012)

Benzodiazepines and benzotriazepines as protein interaction inhibitors targeting bromodomains of the BET family
ανά: Filippakopoulos, P, κ.ά.
Έκδοση: (2012)

Selective inhibition of BET bromodomains.
ανά: Filippakopoulos, P, κ.ά.
Έκδοση: (2010)

Selective inhibition of BET bromodomains.
ανά: Filippakopoulos, P, κ.ά.
Έκδοση: (2010)

Chemical probes and inhibitors of bromodomains outside the BET family
ανά: Moustakim, M, κ.ά.
Έκδοση: (2016)

Discovery and Optimization of Small-Molecule Ligands for the CBP/p300 Bromodomains
ανά: Hay, D, κ.ά.
Έκδοση: (2014)

Bromodomain-peptide displacement assays for interactome mapping and inhibitor discovery.
ανά: Philpott, M, κ.ά.
Έκδοση: (2011)

Bromodomain-peptide displacement assays for interactome mapping and inhibitor discovery.
ανά: Philpott, M, κ.ά.
Έκδοση: (2011)

Assessing cellular efficacy of bromodomain inhibitors using fluorescence recovery after photobleaching
ανά: Philpott, M, κ.ά.
Έκδοση: (2014)

PFI-1, a highly selective protein interaction inhibitor, targeting BET Bromodomains.
ανά: Picaud, S, κ.ά.
Έκδοση: (2013)

Small-molecule bromodomain inhibitors for cancer therapy
ανά: Qi, J, κ.ά.
Έκδοση: (2010)

3,5-Dimethylisoxazoles inhibit the bromodomain-histone protein-protein interaction
ανά: Hewings, D, κ.ά.
Έκδοση: (2012)

Promiscuous targeting of bromodomains by Bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia
ανά: Picaud, S, κ.ά.
Έκδοση: (2016)

Evaluation of linker length effects on a BET bromodomain probe
ανά: Traquete, R, κ.ά.
Έκδοση: (2019)

3,5-dimethylisoxazoles act as acetyl-lysine-mimetic bromodomain ligands.
ανά: Hewings, D, κ.ά.
Έκδοση: (2011)

The bromodomain interaction module.
ανά: Filippakopoulos, P, κ.ά.
Έκδοση: (2012)

The bromodomain interaction module
ανά: Filippakopoulos, P, κ.ά.
Έκδοση: (2012)

3,5-dimethylisoxazoles act as acetyl-lysine-mimetic bromodomain ligands
ανά: Hewings, D, κ.ά.
Έκδοση: (2011)

Developing small molecule inhibitors of the CREBBP bromodomain-histone interaction
ανά: Rooney, T, κ.ά.
Έκδοση: (2012)

Discovery of BET bromodomain inhibitors and their role in target validation
ανά: Mueller, S, κ.ά.
Έκδοση: (2014)

Bromodomains as therapeutic targets.
ανά: Muller, S, κ.ά.
Έκδοση: (2011)

Stimulation of Hepatic Apolipoprotein A-I Production by Novel Thieno-Triazolodiazepines: Roles of the Classical Benzodiazepine Receptor, PAF Receptor, and Bromodomain Binding.
ανά: Kempen, H, κ.ά.
Έκδοση: (2013)

BET bromodomain ligands: Probing the WPF shelf to improve BRD4 bromodomain affinity and metabolic stability
ανά: Jennings, L, κ.ά.
Έκδοση: (2018)

Targeting bromodomains: epigenetic readers of lysine acetylation.
ανά: Filippakopoulos, P, κ.ά.
Έκδοση: (2014)

Synthesis and biological investigation of (+)-JD1, an organometallic BET bromodomain inhibitor
ανά: Hassell-Hart, S, κ.ά.
Έκδοση: (2019)

Dual kinase-bromodomain inhibitors for rationally designed polypharmacology.
ανά: Ciceri, P, κ.ά.
Έκδοση: (2014)

Optimization of 3,5-dimethylisoxazole derivatives as potent bromodomain ligands.
ανά: Hewings, D, κ.ά.
Έκδοση: (2013)

Corrigendum: Dual kinase-bromodomain inhibitors for rationally designed polypharmacology.
ανά: Ciceri, P, κ.ά.
Έκδοση: (2014)

Histone recognition and large-scale structural analysis of the human bromodomain family.
ανά: Filippakopoulos, P, κ.ά.
Έκδοση: (2012)

Selective targeting of the BRG/PB1 bromodomains impairs embryonic and trophoblast stem cell maintenance.
ανά: Fedorov, O, κ.ά.
Έκδοση: (2015)

A series of potent CREBBP bromodomain ligands reveals an induced-fit pocket stabilized by a cation-π interaction
ανά: Rooney, T, κ.ά.
Έκδοση: (2014)

Effect of BET missense mutations on bromodomain function, inhibitor binding and stability
ανά: Lori, L, κ.ά.
Έκδοση: (2016)

Interactome rewiring following pharmacological targeting of BET bromodomains
ανά: Lambert, J-P, κ.ά.
Έκδοση: (2018)

Maintenance of muscle myosin levels in adult C. elegans requires both the double bromodomain protein BET-1 and sumoylation.
ανά: Fisher, K, κ.ά.
Έκδοση: (2013)

Dissecting the Role of BET Bromodomain Proteins BRD2 and BRD4 in Human NK Cell Function
ανά: Cribbs, AP, κ.ά.
Έκδοση: (2021)