A comprehensive model for assessment of liver stage therapies targeting Plasmodium vivax and Plasmodium falciparum

Malaria liver stages represent an ideal therapeutic target with a bottleneck in parasite load and reduced clinical symptoms; however, current in vitro pre-erythrocytic (PE) models for Plasmodium vivax and P. falciparum lack the efficiency necessary for rapid identification and effective evaluation o...

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Bibliographic Details
Main Authors: Roth, A, Maher, SP, Conway, AJ, Ubalee, R, Chaumeau, V, Andolina, C, Kaba, SA, Vantaux, A, Bakowski, MA, Luque, RT, Adapa, SR, Singh, N, Barnes, SJ, Cooper, CA, Rouillier, M, McNamara, CW, Mikolajczak, SA, Sather, N, Witkowski, B, Campo, B, Kappe, SHI, Lanar, DE, Nosten, F, Davidson, S, Jiang, RHY, Kyle, DE, Adams, JH
Format: Journal article
Language:English
Published: Nature Publishing Group 2018