A comparison of existing and new methods for Torsade de Pointes risk classification based on multi-ion channel screening
omputational methods for predicting Torsades de Pointes (TdP) risk commonly use ion channel data for three currents: IKr, INa and ICaL. Here we investigated whether using screening data for additional currents (INaL, IKs, Ito and IK1) improves predictions. We used a recent manual patch-clamp dataset...
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| Format: | Conference item |
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Elsevier
2017
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