Enriched enrollment: definition and effects of enrichment and dose in trials of pregabalin and gabapentin in neuropathic pain. A systematic review.

AIMS: Enriched enrollment study designs have been suggested to be useful for proof of concept when only a proportion of the diseased population responds to a treatment intervention. We aim to investigate whether this really is the case in trials of pregabalin and gabapentin in neuropathic pain. MET...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors: Straube, S, Derry, S, McQuay, H, Moore, R
Format: Journal article
Sprog:English
Udgivet: 2008