High level of PD-1 expression on hepatitis C virus (HCV)-specific CD8+ and CD4+ T cells during acute HCV infection, irrespective of clinical outcome.
We monitored expression of PD-1 (a mediator of T-cell exhaustion and viral persistence) on hepatitis C virus (HCV)-specific CD8(+) and CD4(+) T cells from blood and liver during acute and chronic infections and after the resolved infection stage. PD-1 expression on HCV-specific T cells was high earl...
Päätekijät: | , , , , , , , , , , , , , , , , , , , |
---|---|
Aineistotyyppi: | Journal article |
Kieli: | English |
Julkaistu: |
2008
|