Synthesis of (+)-obtusenyne

An enantioselective synthesis of the halogenated medium-ring ether natural product (+)-obtusenyne is reported which uses the ring expansion of a seven-membered ketene acetal by means of a Claisen rearrangement to construct the core nine-membered oxygen heterocycle. The trans substituents across the...

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Bibliografski detalji
Glavni autori: Mak, S, Curtis, N, Payne, A, Congreve, MS, Wildsmith, A, Francis, C, Davies, J, Pascu, S, Burton, J, Holmes, AB
Format: Journal article
Jezik:English
Izdano: Wiley 2008