Nucleic acid base analog FRET-pair facilitating detailed structural measurements in nucleic acid containing systems.

We present the first nucleobase analog fluorescence resonance energy transfer (FRET)-pair. The pair consists of tC(O), 1,3-diaza-2-oxophenoxazine, as an energy donor and the newly developed tC(nitro), 7-nitro-1,3-diaza-2-oxophenothiazine, as an energy acceptor. The FRET-pair successfully monitors di...

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Bibliographic Details
Main Authors: Börjesson, K, Preus, S, El-Sagheer, A, Brown, T, Albinsson, B, Wilhelmsson, L
Format: Journal article
Language:English
Published: 2009