The effects of GABA(B) agonists and gabapentin on mechanical hyperalgesia in models of neuropathic and inflammatory pain in the rat.

We have examined the effects of a novel GABA(B) agonist, CGP35024, in models of chronic neuropathic (partial sciatic ligation) and inflammatory (Freund's complete adjuvant) pain in the rat, and its inhibitory action on spinal transmission in vitro. The effects of CGP35024 were compared with L-b...

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Bibliographic Details
Main Authors: Patel, S, Naeem, S, Kesingland, A, Froestl, W, Capogna, M, Urban, L, Fox, A
Format: Journal article
Language:English
Published: 2001