L-DMDP, L-homoDMDP and their C-3 fluorinated derivatives: synthesis and glycosidase-inhibition.

L-DMDP and L-homoDMDP, the enantiomers of naturally occurring DMDP and homoDMDP have been synthesized from D-xylose derived cyclic nitrone 9. Their 3-deoxy-3-fluorinated analogues were also obtained from polyhydroxylated fluorinated cyclic nitrone 10, which was prepared from fluorinated sugar 12 in...

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Bibliographic Details
Main Authors: Li, Y, Huang, M, Yamashita, Y, Kato, A, Jia, Y, Wang, W, Fleet, G, Nash, R, Yu, C
Format: Journal article
Language:English
Published: 2011