L-DMDP, L-homoDMDP and their C-3 fluorinated derivatives: synthesis and glycosidase-inhibition.

Eitemau Tebyg

• SYNTHESIS AND EFFECTS ON HUMAN LIVER GLYCOSIDASES OF 6-DEOXY-DMDP
  gan: Hughes, D, et al.
  Cyhoeddwyd: (1993)
• NATURAL AND SYNTHETIC GLYCOSIDES OF DMDP
  gan: Hindle, N, et al.
  Cyhoeddwyd: (1995)
• Looking glass inhibitors: scalable syntheses of DNJ, DMDP, and (3R)-3-hydroxy-L-bulgecinine from D-glucuronolactone and of L-DNJ, L-DMDP, and (3S)-3-hydroxy-D-bulgecinine from L-glucuronolactone. DMDP inhibits beta-glucosidases and beta-galactosidases whereas L-DMDP is a potent and specific inhibitor of alpha-glucosidases
  gan: Best, D, et al.
  Cyhoeddwyd: (2010)
• C-branched iminosugars: α-glucosidase inhibition by enantiomers of isoDMDP, isoDGDP, and isoDAB-L-isoDMDP compared to miglitol and miglustat.
  gan: Jenkinson, S, et al.
  Cyhoeddwyd: (2013)
• Looking glass inhibitors: L-DMDP, a more potent and specific inhibitor of α-glucosidases than the enantiomeric natural product DMDP
  gan: Yu, C, et al.
  Cyhoeddwyd: (2004)